
Resveratrol (3,5,4'-trihydroxy-trans-stilbene), is a non-flavonoid polyphenol [6] naturally occurring in several foods and plants as red grapes (Vitis vinifera), where it is primarily found in the skin but also in its seeds, and also in the roots of hellebore (Veratrum album), from where it was originally isolated by Takaoka back in 1940 [7], and in more than other 70 plant species, among which we can mention berries and peanuts [1].
In spite nowadays it is widely known that Resveratrol may exert many health benefits, as for example stop breast cancer cell growth, increase longevity, be cardioprotective, neuroprotective [2], to treat pain, inflammation, tissue injury and even beneficial against coronary heart disease [1], something that was only found back in 1992, to reduce the risk of neurodegenerative diseases as Alzheimer's disease and since now another one, its susceptibility to be used as a radiation enhancer in the treatment of prostate cancer cells.
A University of Missouri researcher has discovered that Resveratrol can make prostate tumor cells more susceptible to radiation treatment, increasing the chances of a full recovery from all types of prostate cancer, including aggressive tumors. Image: Red grapes by Danny Molyneux under Creative Common license (CC BY 2.0).
Formula: 3,5,4'-trihydroxy-trans-stilbene
Occurrence: Red grapes, berries, peanuts, hellebore