Epigallocatechin-3-gallate (EGCG), a green tea polyphenol with anticancer properties, was already known for its capability to inhibit carcinogenesis , in spite the mechanism how EGCG achieved this wasn't still completely clear.
It seems that EGCG affects multiple biological pathways , one of the ways these polyphenols achieve their anti-cancerous properties in multiple types of cancers. However one of the reasons why researchers couldn't profit from its anti-cancer properties was the inability to specifically reach tumors deploying EGCG via intravenous administration , so the deployment of EGCG in the blood stream didn't reach the cancer cells and couldn't be effectevely used against them. Image left: Tea plantation by sarahemcc under Creative Commons License (CC BY 2.0).
Now, a group of researchers from the Universities of Strathclyde and Glasgow, have discovered an effective way of deploying EGCG in a way that it will be able to effectively reach its target, cancer cells .
The research showed very promissing results, with two-thirds of tumours treated with this new method shrinking or disappearing withing one month of treatment with no side effects to normal tissues . But how did they achieve EGCG to be deployed so effectevely to cancer cells?
Common name: Green tea