Plumbago zeylanica, commonly known as Chitrak, is an herbaceous plant that has been deeply researched for its anti-cancer properties, properties which are thought to be exerted due to the high content of Plumbagin, an active constituent found in Plumbago zeylanica, Juglans regia (English Walnut), Juglans cinerea (whitenut) and Juglans nigra (blacknut) .
Now, a group of scientists and researchers from the Department of Human Oncology, University of Wisconsin, have discovered how Plumbagin, a quinoid constituent isolated from the roots of the medicinal plant Plumbago zeylanica used in Indian and Chinese systems of medicine for more than 2,500 years for the treatment of various types of ailments , inhibits in vivo prostate cancer development in the transgenic adenocarcinoma of mouse prostate .
The Department of Human Oncology, University of Wisconsin, were the first ones to publish in another study in 2008 how plumbagin inhibited the growth and invasion of hormone refractory prostate cancer cells . Image left: Plumbago zeylanica by Latihamba under Creative Commons License (CC BY 2.0).
Common name: Ceylon leadwort, Doctorbush [5,6], Chitrak.