Ganoderma tsugae, a mushroom with many properties (video)
Health benefits of Ganoderma mushroom
Ganoderma tsugae is a medicinal fungus with several biological activities  known as Hemlock varnish shelf mushroom [2,4], Lingzhi or Reishi , that usually grows in conifers, mainly in hemlocks , where its common name comes from. It has been used as a folk remedy for the promotion of health and longevity in China and other oriental countries  and has recently been in the scope of scientists and researchers for its multiple medicinal properties and a source of active constituents that exert anti-angiogenic (avoids the growth of blood vessels) effects , something that can be used as a potential source for new anti-cancer medicines. Image: Ganoderma tsugae by Jason Hollinger under Creative Commons license (CC BY 2.0)
In spite the woody nature Ganoderma tsugae makes this mushroom not edible , several species of Ganoderma are currently cultivated for use in coffee, teas, and dietary supplements . In Asia, Ganoderma have been traditionally administered throughout Asia for centuries as a cancer treatment and for other medicinal purposes .
Common name: Hemlok varnish shelf mushroom, Sung-shan-ling-chih, Songshan lingzhi, Lingzhi, Reishi.
INFO: Ganoderma tsugae (GT) is a traditional Chinese medicine that exhibits significant anti-tumor activities against many types of cancer .
GANODERMA TSUGAE EXTRACT INHIBITS COLORECTAL CANCER CELL GROWTH
At least in one study done on tumorigenesis in nude mice on the inhibitory activity and molecular mechanisms of anti-tumor effect on colorectal cancer cells of Ganoderma tsugae, it was shown how Ganoderma tsugae extracts inhibit colorectal cancer cell proliferation caused by accumulating cells in G(2)/M phase, something that may lead to a possible therapeutic use of Ganoderma tsugae for treating colorectal cancer .
GANODERMA TSUGAE AND LUNG ADENOCARCINOMA
It another study it was also noted that the fungal immunomodulatory protein from Ganoderma tsugae (reFIP-gts) had anti-telomerase effects in human lung adenocarcinoma A549 cells, something that suggests that the use of Ganoderma tsugae reFIP-gts protein may be a powerful new strategy for chemoprevention and antineoplastic therapy .
GANODERMA TSUGAE AND BRONCHOALVEOLAR INFLAMMATION
Ganoderma tsugae, known in China as Songshan lingzhi, is cultivated in Taiwan and has been extensively used in Chinese traditional medicine to treat different diseases. In a study performed to investigate its properties to alleviate bronchoalveolar inflammation, it was noted that it may help to alleviate inflammation via decreasing the infiltration of inflammatory cells .
GANODERMA TSUGAE ANTIOXIDANT PROPERTIES
Out of three species studied of Ganoderma, namely the Ganoderma lucidum (Ling-chih), Ganoderma tsugae (Sung-shan-ling-chih), and Coriolus versicolor (Yun-chih) Overall, the Ganoderma lucidum and Ganoderma tsugae were higher in antioxidant activity .
SKIN WOUND HEALING WITH SACCHACHITIN A WEAVABLE SKIN SUBSTITUTE FROM THE FRUITING BODY OF GANODERMA TSUGAE
Sacchachitin, a weavable skin substitute made from the residual fruiting body of Ganoderma tsugae, has been demonstrated to promote skin wound healing . In spite the study of reference, performed in rats, showed that the subcutaneous injection of Sacchachitin caused local acute inflammation, the wound area covered by Sacchachitin completely healed by 21 days, while that covered with cotton gauze did not , significantly enhancing the proliferation and migration of fibroblast cells [14,15].