Capsaicin is responsible for the hot taste given by hot peppers being the amount of capsaicin in hot peppers directly proportional to their intensity, ranging from the zero level in the Scoville scale of the mild Bell chili peppers to the Naga Jolokia reaching approx. 950,000. But something that not many people knew until now is the effects that capsaicin may have on cancer cells in certain types of cancers.
Chemical Formula: C18H27NO3
Sources: Hot peppers
CURIOSITY! Capsaicin is insoluble in water, that means that drinking water after having eaten a Chili pepper won't help, but it does dissolve in milk or fatty foods so you can try with bread instead.
CAPSAICIN FOR BREAST CANCER AND LEUKEMIA
Capsaicin was able, for example, to induce a significant growth arrest and apoptosis in human breast cancer and leukemia cancer cells in vitro . In another study  where traditional medicinal plants were investigated for their claimed anti-cancerous properties, showed that out of 84 medicinal plants used for their anti-cancerous properties (Aloe vera, Euphorbia tirucalli, and Tabebuia impetiginosa), capsaicin was found to be one of the most recurrent molecules among all active constituents found in those herbs, together with lapachone, silibiniin, β-lapachone and plumbagin.
But breast cancer and leukemia are not the only types of cancer on which capsaicin has shown to be effective, in breast cancer capsaicin was found to inhibit cancer cell growth in caspase-3-deficient human breast cancer cells , and in human colon cancer colo 205 cells capsaicin was able to increase the levels of pro-apoptotic proteins. The last one where it showed also a certain effectiveness was tongue cancer cells .
As downside there are other studies claiming the cancerous effect of capsaicin , claiming that long-term topical application of capsaicin can increase skin carcinogenesis in mice.
CAPSAICIN FOR HERPES ZOSTER (SHINGLES) AND POSTHERPETIC NEURALGIA
The use of capsaicin has also been studied in the treatment of herpes zoster (shingles) and postherpetic neuralgia. In one of the studies on the subject capsaicin was found to be able to shorten the duration of acute herpes zoster and alleviate the pain of postherpetic neuralgia. In both cases capsaicin cream offered moderate pain relief to patients that suffered from postherpetic neuralgia .
CAPSAICIN INCREASES FACIAL SKIN ELASTICITY AND PROMOTES HAIR GROWTH
In another study on the effects of capsaicin on skin elasticity, it was reported that topical application of capsaicin increases facial skin elasticity. Additionally it was also discovered that topical application of capsaicin promoted hair growth by increasing dermal insulin-like growth factor-I (IGF-I) .