Apigenin, a natural flavonoid from Chamomile and cancer
Herbs and their anti-cancer properties
There are many herbs and herbal remedies said to have beneficial effects for the treatment of cancer, but not all of them have scientific based studies to corroborate with evidence if what they claim has a scientific and solid ground. On this article we will refer to Apigenin, a natural flavonoid found in many herbs, as for example Chamomile (Anthemis nobilis), as well as in apples, celery and also in some spices as oregano, tarragon, cilantro, basil and parsley.
There are many herbs and herbal remedies said to have beneficial effects on the treatment of cancer, but not all of them have scientific based studies to corroborate with evidence if what they claim has a scientific and solid ground. On this article we will refer to Apigenin, a natural flavonoid found in many herbs, as for example Chamomile (Anthemis nobilis), as well as in apples, celery and also in some spices as oregano, tarragon, cilantro, basil and parsley.
Chamomile (Anthemis nobilis) has been used since more than two thousand years ago to treat menstrual problems, gall bladder, fevers, inflammations, gastrointestinal disorders, as an relaxing infusion and as antiseptic.
One of its active constituents, apigenin, is a flavonoid believed to have some influence over the mild sedative effects claimed by this herb. In recent scientific studies, this flavonoid, apigenin, was found to also act as an anti-inflammatory agent . The National Toxicology Program from the US Government cited in one of its articles:
Pure apigenin is used primarily in research as a protein kinase inhibitor that may suppress tumour promotion and that has anti-proliferating effects
Scientific evidence was found about the benefits of apigenin on the suppression of cancer cells. In a study carried out by the UC Riverside biochemists published in the on-line edition of the National Academy of Sciences , Xuan Liu, professor of biochemistry, and Xin Cai, a post-doctoral researcher, found that apigenin is able to find the protein p53, a well known tumor suppressor that acts as an anti-cancerous agent by stopping cancer cells growth and killing them.
The study reveals how apigenin, a flavonoid found in chamomile, parsley and other herbs and vegetables, is also able to not only locate the protein p53 but also to bring it to the cell nucleus where it is able to stop the cell growth in those cases in which the cell DNA has been damaged by cancer.
The preventive use of apigenin from natural sources seems therefore to be also recommended taking into consideration the results of this study.
 Pubmed: Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin.
Funakoshi-Tago M, Nakamura K, Tago K, Mashino T, Kasahara T.
Department of Biochemistry, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan.
 National Toxicology Program. NIH-sponsored study by UC Riverside biochemists published in the online edition of teh National Academy of Sciences
- Tags: ANTHEMIS NOBILIS, ANTHEMIS ODORATA, ANTI-CANCER, BREAST CANCER, CAMOMILLE ROMAINE, CANCER, CHAMAEMELUM NOBILE, CHAMOMILLA NOBILIS, CHINESE: 果香菊, DANISH: ROMERSK KAMILLE, DUTCH: DUBBELE KAMILLE, ENGLISH: ENGLISH CHAMOMILE, FINNISH: JALOSAURAMO, FRENCH: CAMOMILLE NOBLE, GARDEN CHAMOMILE, GARTENKAMILLE, GERMAN: EDELKAMILLE, HERBAL REMEDIES, ITALIAN: CAMOMILLA ROMANA, JAPANESE: ローマンカモミール ROOMAN KAMOMIIRU, KAMILLE ROMERSK, MAAGBLOEMPJE, MANZANILLA AMARGA, MANZANILLA FINA, MANZANILLA ROMANA, MATRICARIA, NOBILIS, NOBLE CHAMOMILE, NORWEGIAN: KAMILLE, ORMENIS NOBILIS, POLISH: RUMIAN SZLACHETNY, PORTUGUESE: MACELA-DOURADA, PROSTATE CANCER, ROMAN CHAMOMILE, ROMERKAMILLE, ROMERSK KAMILLE, ROMERSK KAMOMILL, RÖMISCHE KAMILLE, RÖMISCHER ROMEY, ROOMALAINEN KAMOMILLA, ROOMSE KAMILLE, RUSSIAN CHAMOMILE, RUSSIAN: ПУПАВКА БЛАГОРОДНАЯ PUPAVKA BLAGORODNAIA, SPANISH: CAMOMILA DE JARDÍN, SWEDISH: KAMILLKULLA, TRÄDGÅRDSKULLA, VIETNAMESE: CÂY CÚC CAM, ПУПАВКА РИМСКАЯ PUPAVKA RIMASKAIA, РИМСКАЯ РОМАШКА RIMSKAIA ROMASHKA, РОМАШКА БЛАГОРОДНАЯ ROMASHKA BLAGORODNAIA, РОМАШКА РИМСКАЯ ROMASHKA RIMSKAIA