Chaste tree (Vitex agnus castus) for the treatment of menopausal symptoms
Vitex agnus castus (Chaste tree) has been used since centuries ago for the treatment of women's related health problems, from menstrual and premenstrual dysphoric disorder (PMDD)  to physiological conditions as the menopausal symptoms .
In spite some of these affections will have a permanent character, as the endocrine changes suffered by menopausal women, caused by the hormonal changes and consider irreversible as part of this natural change, some others as the menopausal symptoms described by some women, i.e. hot flushes, will usually disappear over the time or if duly treated.
Common name: Vitex, Chaste Tree, Chasteberry, Abraham's Balm or Monk's Pepper
Some research done on herbs as Vitex agnus castus (Castle tree) shows how Chaste tree, as well as some others as Ginkgo biloba, Crocus sativus and black cohosh have been some of the most documented herbs for its benefits and for the different uses it has been given on women related problems and affections, some of them as common as the ones mentioned above.
VITEX AGNUS CASTUS ACTIVE CONSTITUENTS
But where are Vitex agnus castus (Chaste tree or chasteberry) health benefits coming from?
These wonderful properties exerted by this herb may simply be given by some of the active constituents found on it, among which we can mention two labdane-type diterpenoids, seven labdane-type diterpenoids, one halimane-type diterpenoid, two oleanane-type triterpenoids, two ursane-type triterpenoids, one aromadendrane-type sesquiterpenoid and one flavonoid.
VITEX AGNUS CASTUS FOR MENOPAUSE SYMPTOMS
Several clinical trials and essays reported about these health benefits, some of them include for example the treatment of premenstrual syndrome, a condition of cyclical and recurrent physical and psychological discomfort occurring 1 to 2 weeks before menstrual period .
Castle tree has proven to be more effective for the treatment of premenstrual syndrome than placebo . There was only one of the premenstrual syndrome symptoms for which Castle tree seemed to be less effective, lower abdominal cramping, for which it didn't show to be of much help .
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 [Psychic aspects of the premenstrual dysphoric disorders. New therapeutic strategies: our experience with Vitex agnus castus.]
[Article in Italian]
Ciotta L, Pagano I, Stracquadanio M, Di Leo S, Andò A, Formuso C.
Istituto di Patologia Ostetrica e Ginecologica, Universitàdegli Studi di Catania, Catania, Italia
 Menopausal symptoms.
Burbos N, Morris EP.
Norfolk and Norwich University Hospital, Norwich, UK.
 A new diterpenoid glucoside and two new diterpenoids from the fruit of Vitex agnus-castus.
Ono M, Eguchi K, Konoshita M, Furusawa C, Sakamoto J, Yasuda S, Ikeda T, Okawa M, Kinjo J, Yoshimitsu H, Nohara T.
School of Agriculture, Tokai University, Kumamoto, Japan.
 Herbal treatments for alleviating premenstrual symptoms: a systematic review.
Dante G, Facchinetti F.
Mother Infant Department, University of Modena and Reggio Emilia, Via del Pozzo 71, Modena, Italy.
Anti-inflammatory and enzyme inhibitory activities of a crude extract and a pterocarpan isolated from the aerial parts of Vitex agnus-castus.
Ahmad B, Azam S, Bashir S, Khan I, Adhikari A, Choudhary MI.
Center for Biotechnology and Microbiology University of Peshawar, Peshawar, Pakistan
 Therapeutic management of premenstrual syndrome.
Departments of Obstetrics/Gynecology and Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
 Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women.
Ma L, Lin S, Chen R, Zhang Y, Chen F, Wang X.
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science.
 Effects of a combination of Hypericum perforatum and Vitex agnus-castus on PMS-like symptoms in late-perimenopausal women: findings from a subpopulation analysis.
van Die MD, Bone KM, Burger HG, Reece JE, Teede HJ.
Royal Melbourne Institute of Technology University, Bundoora, Victoria, Australia
 Vitex agnus-castus (Chaste-Tree/Berry) in the treatment of menopause-related complaints.
van Die MD, Burger HG, Teede HJ, Bone KM.
Royal Melbourne Institute of Technology (RMIT) University, Bundoora, Victoria, Australia
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